I was wondering at what step is the covariates applied during the computation. Is it already applied while computing measures? Or only while comparing them? I mean are the network measures computed on the residuals or it is used as ANCOVA for comparison?
If you are using a structural pipeline, you can adjust for covariates by selecting the partial Pearson correlation or partial Spearman correlation when creating the graph/network. If you do not select one of these options, covariates won’t be used in the analysis.
Thank you for your response. Yes, I select the Pearson with covariates. My question was rather when exactly during the processing the covariates are applied when I select this option. So, is the process as follows true ?
The pearson correlation matrices for each group is created considering the covariates (or using residual).
These matrices are then used to compute the network measures.