Effect of Covariates in the measures

[Nabin Koirala]

Hi BRAPH team,

I was wondering at what step is the covariates applied during the computation. Is it already applied while computing measures? Or only while comparing them? I mean are the network measures computed on the residuals or it is used as ANCOVA for comparison?

Thank you.

Best,
Nabin

[Anna Canal-Garcia]

Hi Nabin,

If you are using a structural pipeline, you can adjust for covariates by selecting the partial Pearson correlation or partial Spearman correlation when creating the graph/network. If you do not select one of these options, covariates won’t be used in the analysis.

[Nabin Koirala]

Hi Anna,

Thank you for your response. Yes, I select the Pearson with covariates. My question was rather when exactly during the processing the covariates are applied when I select this option. So, is the process as follows true ?

1. The pearson correlation matrices for each group is created considering the covariates (or using residual).
2. These matrices are then used to compute the network measures.

Sorry if I am not being clear.

Best,
Nabin

[Anna Canal-Garcia]

Hi Nabin,

Yes, if you select partial Pearson correlation, the covariates are considered then. So, before measures are calculated.

Best regards,
Anna

[Nabin Koirala]

Thanks! that’s what I wanted to know.

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